# SBOM for genomeshader 0.3.1

The Python package genomeshader 0.3.1 ships 3 SBOM files (CycloneDX) inside its wheels, under `.dist-info/sboms/` ([PEP 770](https://peps.python.org/pep-0770/)). Its wheels carry a verified PEP 740 attestation.

- Package URL (PURL): `pkg:pypi/genomeshader@0.3.1`
- PyPI: https://pypi.org/project/genomeshader/0.3.1/
- Homepage: <https://github.com/broadinstitute/genomeshader>

## SBOMs

### genomeshader-0.3.1-cp37-abi3-macosx\_10\_12\_x86\_64.whl

PEP 740 attestation verified (GitHub, broadinstitute/genomeshader, workflow publish.yml).

- [genomeshader-0.3.1.dist-info/sboms/genomeshader.cyclonedx.json](https://pypi.sbomify.com/artifact/32c688f6-56e2-537d-9cef-5dc384df328f/download): CycloneDX/1.5, `application/vnd.cyclonedx+json`, valid, 69 known vulnerabilities

### genomeshader-0.3.1-cp37-abi3-macosx\_11\_0\_arm64.whl

PEP 740 attestation verified (GitHub, broadinstitute/genomeshader, workflow publish.yml).

- [genomeshader-0.3.1.dist-info/sboms/genomeshader.cyclonedx.json](https://pypi.sbomify.com/artifact/6c147cfb-d00e-5e73-93ad-d8360743d956/download): CycloneDX/1.5, `application/vnd.cyclonedx+json`, valid, 69 known vulnerabilities

### genomeshader-0.3.1-cp37-abi3-manylinux\_2\_17\_x86\_64.manylinux2014\_x86\_64.whl

PEP 740 attestation verified (GitHub, broadinstitute/genomeshader, workflow publish.yml).

- [genomeshader-0.3.1.dist-info/sboms/genomeshader.cyclonedx.json](https://pypi.sbomify.com/artifact/7dda8264-b5a2-581b-9fc9-2fe5196cdaac/download): CycloneDX/1.5, `application/vnd.cyclonedx+json`, valid, 69 known vulnerabilities

## Known vulnerabilities

Components listed in these SBOMs, matched against the [OSV database](https://osv.dev/) as of 2026-11-10.

| Vulnerability | Severity | Component | Fixed in | Summary |
|---|---|---|---|---|
| [CVE-2026-42327](https://insights.sbomify.com/CVE-2026-42327/) | high (8.7) | openssl 0.10.63 (crates.io) | 0.10.79 | rust-openssl has undefined behavior in X509Ref::ocsp\_responders for certificates with non-UTF-8 OCSP URLs |
| [GHSA-36hh-v3qg-5jq4](https://osv.dev/vulnerability/GHSA-36hh-v3qg-5jq4) | high (8.7) | pyo3 0.20.2 (crates.io) | 0.29.0 | PyO3 has an Out-of-bounds Read in \`nth\` / \`nth\_back\` for \`PyList\` and \`PyTuple\` iterators |
| [CVE-2026-41898](https://insights.sbomify.com/CVE-2026-41898/) | high (8.3) | openssl 0.10.63 (crates.io) | 0.10.78 | rust-openssl: Unchecked callback length in PSK/cookie trampolines leaks adjacent memory to peer |
| [CVE-2026-41681](https://insights.sbomify.com/CVE-2026-41681/) | high (8.1) | openssl 0.10.63 (crates.io) | 0.10.78 | rust-openssl: rustMdCtxRef::digest\_final() writes past caller buffer with no length check |
| [CVE-2024-27308](https://insights.sbomify.com/CVE-2024-27308/) | high (7.5) | mio 0.8.10 (crates.io) | 0.8.11 | Tokens for named pipes may be delivered after deregistration |
| [RUSTSEC-2026-0194](https://osv.dev/vulnerability/RUSTSEC-2026-0194) | high (7.5) | quick-xml 0.31.0 (crates.io) | 0.41.0 | Quadratic run time when checking a start tag for duplicate attribute names |
| [RUSTSEC-2026-0195](https://osv.dev/vulnerability/RUSTSEC-2026-0195) | high (7.5) | quick-xml 0.31.0 (crates.io) | 0.41.0 | Unbounded namespace-declaration allocation in \`NsReader\` enables memory-exhaustion denial of service |
| [CVE-2026-93599](https://insights.sbomify.com/CVE-2026-93599/) | high (7.5) | rustls-webpki 0.101.7 (crates.io) | 0.103.13 | Reachable panic in certificate revocation list parsing |
| [CVE-2026-41676](https://insights.sbomify.com/CVE-2026-41676/) | high (7.2) | openssl 0.10.63 (crates.io) | 0.10.78 | rust-openssl: Deriver::derive and PkeyCtxRef::derive can overflow short buffers on OpenSSL 1.1.1 |
| [CVE-2026-41678](https://insights.sbomify.com/CVE-2026-41678/) | high (7.2) | openssl 0.10.63 (crates.io) | 0.10.78 | Out-of-bounds write in \`aes::unwrap\_key\` |
| [RUSTSEC-2024-0357](https://osv.dev/vulnerability/RUSTSEC-2024-0357) | medium (6.9) | openssl 0.10.63 (crates.io) | 0.10.66 | \`MemBio::get\_buf\` has undefined behavior with empty buffers |
| [CVE-2026-25727](https://insights.sbomify.com/CVE-2026-25727/) | medium (6.8) | time 0.3.44 (crates.io) | 0.3.47 | Denial of Service via Stack Exhaustion |
| [CVE-2025-4432](https://insights.sbomify.com/CVE-2025-4432/) | medium (6.6) | ring 0.16.20 (crates.io) | 0.17.12 | Some AES functions may panic when overflow checking is enabled. |
| [CVE-2025-4432](https://insights.sbomify.com/CVE-2025-4432/) | medium (6.6) | ring 0.17.7 (crates.io) | 0.17.12 | Some AES functions may panic when overflow checking is enabled. |
| [CVE-2024-12224](https://insights.sbomify.com/CVE-2024-12224/) | medium (6.3) | idna 0.5.0 (crates.io) | 1.0.0 | \`idna\` accepts Punycode labels that do not produce any non-ASCII when decoded |
| [CVE-2025-24898](https://insights.sbomify.com/CVE-2025-24898/) | medium (6.3) | openssl 0.10.63 (crates.io) | 0.10.70 | ssl::select\_next\_proto use after free |
| [RUSTSEC-2025-0022](https://osv.dev/vulnerability/RUSTSEC-2025-0022) | medium (6.3) | openssl 0.10.63 (crates.io) | 0.10.72 | Use-After-Free in \`Md::fetch\` and \`Cipher::fetch\` |
| [RUSTSEC-2026-0177](https://osv.dev/vulnerability/RUSTSEC-2026-0177) | medium (6.3) | pyo3 0.20.2 (crates.io) | 0.29.0 | Missing \`Sync\` bound on \`PyCFunction::new\_closure\` closures |
| [CVE-2023-49092](https://insights.sbomify.com/CVE-2023-49092/) | medium (5.9) | rsa 0.6.1 (crates.io) | 0.10.0 | Marvin Attack: potential key recovery through timing sidechannels |
| [CVE-2026-25541](https://insights.sbomify.com/CVE-2026-25541/) | medium (5.5) | bytes 1.5.0 (crates.io) | 1.11.1 | Integer overflow in \`BytesMut::reserve\` |
| [CVE-2026-25537](https://insights.sbomify.com/CVE-2026-25537/) | medium (5.5) | jsonwebtoken 7.2.0 (crates.io) | 10.3.0 | jsonwebtoken has Type Confusion that leads to potential authorization bypass |
| [RUSTSEC-2024-0332](https://osv.dev/vulnerability/RUSTSEC-2024-0332) | medium (5.3) | h2 0.3.24 (crates.io) | 0.3.26 | Degradation of service in h2 servers with CONTINUATION Flood |
| [CVE-2026-44662](https://insights.sbomify.com/CVE-2026-44662/) | medium (5.1) | openssl 0.10.63 (crates.io) | 0.10.79 | rust-openssl vulnerable to heap buffer overflow when encrypting with AES key-wrap-with-padding |
| [CVE-2026-45784](https://insights.sbomify.com/CVE-2026-45784/) | medium (5.1) | openssl 0.10.63 (crates.io) | 0.10.80 | rust-openssl: Potential out-of-bounds write in \`CipherCtxRef::cipher\_update\_inplace\` for AES-KW-PAD ciphers |
| [CVE-2024-41178](https://insights.sbomify.com/CVE-2024-41178/) | medium (4.8) | object\_store 0.8.0 (crates.io) | 0.10.2 | Apache Arrow Rust Object Store: AWS WebIdentityToken exposure in log files |
| [CVE-2026-123609](https://insights.sbomify.com/CVE-2026-123609/) | medium (4.0) | rustls 0.21.12 (crates.io) | 0.23.46 | \`Debug\` impls for client session values expose TLS secrets |
| [CVE-2026-123610](https://insights.sbomify.com/CVE-2026-123610/) | low (3.7) | rustls 0.21.12 (crates.io) | 0.23.46 | Rustls: Brotli certificate decompression can allocate an attacker-controlled amount of memory up to 1 GiB before authentication. |
| [CVE-2026-123611](https://insights.sbomify.com/CVE-2026-123611/) | low (3.7) | rustls 0.21.12 (crates.io) | 0.23.46 | Unauthenticated ServerHello can downgrade later connections to classical key exchange |
| [RUSTSEC-2025-0019](https://osv.dev/vulnerability/RUSTSEC-2025-0019) | low (2.9) | array-init-cursor 0.2.0 (crates.io) | 0.2.1 | \`array-init-cursor\` in version 0.2.0 and below is unsound when used with types that implement \`Drop\` |
| [RUSTSEC-2025-0020](https://osv.dev/vulnerability/RUSTSEC-2025-0020) | low (2.9) | pyo3 0.20.2 (crates.io) | 0.24.1 | Risk of buffer overflow in \`PyString::from\_object\` |
| [RUSTSEC-2024-0379](https://osv.dev/vulnerability/RUSTSEC-2024-0379) | low (2.7) | fast-float 0.2.0 (crates.io) | none listed | Multiple soundness issues |
| [CVE-2026-21895](https://insights.sbomify.com/CVE-2026-21895/) | low (2.7) | rsa 0.6.1 (crates.io) | 0.9.10 | rsa crate has potential panic on a prime being equal to 1 |
| [RUSTSEC-2025-0023](https://osv.dev/vulnerability/RUSTSEC-2025-0023) | low (2.7) | tokio 1.35.1 (crates.io) | 1.38.2 | Broadcast channel calls clone in parallel, but does not require \`Sync\` |
| [GHSA-6g2r-675j-hx59](https://osv.dev/vulnerability/GHSA-6g2r-675j-hx59) | low (2.3) | xxhash-rust 0.8.8 (crates.io) | 0.8.16 | xxhash-rust: Safe xxh3 custom-secret API accepts too-short secret in release |
| [CVE-2026-93600](https://insights.sbomify.com/CVE-2026-93600/) | low (2.2) | rustls-webpki 0.101.7 (crates.io) | 0.103.12 | Name constraints for URI names were incorrectly accepted |
| [CVE-2026-93601](https://insights.sbomify.com/CVE-2026-93601/) | low (2.2) | rustls-webpki 0.101.7 (crates.io) | 0.103.12 | Name constraints were accepted for certificates asserting a wildcard name |
| [CVE-2026-41677](https://insights.sbomify.com/CVE-2026-41677/) | low (1.7) | openssl 0.10.63 (crates.io) | 0.10.78 | rust-opennssl has an Out-of-bounds read in PEM password callback when returning an oversized length |
| [RUSTSEC-2025-0056](https://osv.dev/vulnerability/RUSTSEC-2025-0056) | unknown | adler 1.0.2 (crates.io) | none listed | adler crate is unmaintained, use adler2 instead |
| [RUSTSEC-2026-0190](https://osv.dev/vulnerability/RUSTSEC-2026-0190) | unknown | anyhow 1.0.79 (crates.io) | 1.0.103 | Unsoundness in \`Error::downcast\_mut()\` |
| [RUSTSEC-2025-0052](https://osv.dev/vulnerability/RUSTSEC-2025-0052) | unknown | async-std 1.12.0 (crates.io) | none listed | async-std has been discontinued |
| [RUSTSEC-2025-0012](https://osv.dev/vulnerability/RUSTSEC-2025-0012) | unknown | backoff 0.4.0 (crates.io) | none listed | \`backoff\` is unmaintained. |
| [RUSTSEC-2026-0204](https://osv.dev/vulnerability/RUSTSEC-2026-0204) | unknown | crossbeam-epoch 0.9.18 (crates.io) | 0.9.20 | Invalid pointer dereference in \`fmt::Pointer\` impl for \`Atomic\` and \`Shared\` when the underlying pointer is invalid |
| [RUSTSEC-2026-0387](https://osv.dev/vulnerability/RUSTSEC-2026-0387) | unknown | crypto-bigint 0.3.2 (crates.io) | 0.7.6 | Multiple timing variability issues in operations intended to be constant-time |
| [RUSTSEC-2025-0058](https://osv.dev/vulnerability/RUSTSEC-2025-0058) | unknown | custom\_derive 0.1.7 (crates.io) | none listed | custom\_derive crate is unmaintained |
| [RUSTSEC-2021-0141](https://osv.dev/vulnerability/RUSTSEC-2021-0141) | unknown | dotenv 0.15.0 (crates.io) | none listed | dotenv is Unmaintained |
| [RUSTSEC-2025-0003](https://osv.dev/vulnerability/RUSTSEC-2025-0003) | unknown | fast-float 0.2.0 (crates.io) | none listed | Segmentation fault due to lack of bound check |
| [RUSTSEC-2026-0258](https://osv.dev/vulnerability/RUSTSEC-2026-0258) | unknown | h2 0.3.24 (crates.io) | 0.4.16 | h2 unbounded empty DATA frames |
| [RUSTSEC-2024-0384](https://osv.dev/vulnerability/RUSTSEC-2024-0384) | unknown | instant 0.1.12 (crates.io) | none listed | \`instant\` is unmaintained |
| [RUSTSEC-2026-0418](https://osv.dev/vulnerability/RUSTSEC-2026-0418) | unknown | libz-sys 1.1.15 (crates.io) | 1.1.31 | libz-sys build script leaks environment variables in the build directory |
| [RUSTSEC-2026-0186](https://osv.dev/vulnerability/RUSTSEC-2026-0186) | unknown | memmap2 0.7.1 (crates.io) | 0.9.11 | Unchecked pointer offset in crate \`memmap2\` |
| [RUSTSEC-2025-0119](https://osv.dev/vulnerability/RUSTSEC-2025-0119) | unknown | number\_prefix 0.4.0 (crates.io) | none listed | number\_prefix crate is unmaintained |
| [RUSTSEC-2026-0441](https://osv.dev/vulnerability/RUSTSEC-2026-0441) | unknown | pin-utils 0.1.0 (crates.io) | none listed | \`pin-utils\` is unmaintained |
| [RUSTSEC-2026-0097](https://osv.dev/vulnerability/RUSTSEC-2026-0097) | unknown | rand 0.8.5 (crates.io) | 0.8.6 | Rand is unsound with a custom logger using \`rand::rng()\` |
| [RUSTSEC-2025-0010](https://osv.dev/vulnerability/RUSTSEC-2025-0010) | unknown | ring 0.16.20 (crates.io) | 0.17.0 | Versions of \*ring\* prior to 0.17 are unmaintained. |
| [RUSTSEC-2025-0134](https://osv.dev/vulnerability/RUSTSEC-2025-0134) | unknown | rustls-pemfile 1.0.4 (crates.io) | none listed | rustls-pemfile is unmaintained |
| [CVE-2026-111943](https://insights.sbomify.com/CVE-2026-111943/) | unknown | rustls-webpki 0.101.7 (crates.io) | 0.103.16 | Certificate verification may accept distrusted intermediates |
| [RUSTSEC-2026-0249](https://osv.dev/vulnerability/RUSTSEC-2026-0249) | unknown | smartstring 1.0.1 (crates.io) | none listed | smartstring is unmaintained |
| [RUSTSEC-2026-0386](https://osv.dev/vulnerability/RUSTSEC-2026-0386) | unknown | tokio 1.35.1 (crates.io) | 1.51.6 | \`AsyncFd::new\` and related constructors violate I/O safety |
| [CVE-2026-111943](https://insights.sbomify.com/CVE-2026-111943/) | unknown | webpki-roots 0.25.4 (crates.io) | 0.26.11 | Bundled root certificates allow trust in distrusted emSign intermediates |
| [RUSTSEC-2026-0395](https://osv.dev/vulnerability/RUSTSEC-2026-0395) | unknown | zstd-safe 7.0.0 (crates.io) | 7.4.0 | Use-after-free with \`CParameter::StableInBuffer\` |
| [RUSTSEC-2026-0397](https://osv.dev/vulnerability/RUSTSEC-2026-0397) | unknown | zstd-safe 7.0.0 (crates.io) | 7.4.0 | \`OutBuffer::around\_pos\` exposes uninitialized memory |
| [RUSTSEC-2026-0399](https://osv.dev/vulnerability/RUSTSEC-2026-0399) | unknown | zstd-safe 7.0.0 (crates.io) | 7.4.0 | Use-after-free through \`init\_using\_cdict\` and \`init\_using\_ddict\` |
| [RUSTSEC-2026-0400](https://osv.dev/vulnerability/RUSTSEC-2026-0400) | unknown | zstd-safe 7.0.0 (crates.io) | 7.4.0 | Use-after-free of a dictionary after a one-shot call on a context with an open stream |
| [RUSTSEC-2026-0401](https://osv.dev/vulnerability/RUSTSEC-2026-0401) | unknown | zstd-safe 7.0.0 (crates.io) | 7.4.0 | Out-of-bounds read in \`train\_from\_buffer\` when sample sizes overflow |
| [RUSTSEC-2026-0402](https://osv.dev/vulnerability/RUSTSEC-2026-0402) | unknown | zstd-safe 7.0.0 (crates.io) | 7.4.0 | Heap buffer overflow in \`CCtx::try\_clone\` on a multithreaded context |
| [RUSTSEC-2026-0403](https://osv.dev/vulnerability/RUSTSEC-2026-0403) | unknown | zstd-safe 7.0.0 (crates.io) | 7.4.0 | Uninitialized memory exposed when streaming decompression of a legacy frame fails |
| [RUSTSEC-2026-0404](https://osv.dev/vulnerability/RUSTSEC-2026-0404) | unknown | zstd-safe 7.0.0 (crates.io) | 7.4.0 | Double free in \`DCtx::try\_clone\` |
| [RUSTSEC-2026-0406](https://osv.dev/vulnerability/RUSTSEC-2026-0406) | unknown | zstd-safe 7.0.0 (crates.io) | 7.4.0 | Use-after-free when changing a multithreaded context with an unfinished frame |
| [RUSTSEC-2026-0410](https://osv.dev/vulnerability/RUSTSEC-2026-0410) | unknown | zstd-sys 2.0.9+zstd.1.5.5 (crates.io) | 2.1.2 | WebAssembly allocator shim corrupts memory on allocation failure |

## Fetch it over TEA

This SBOM is served over the [Transparency Exchange API](https://github.com/CycloneDX/transparency-exchange-api) (TEA). With the `libtea` client:

```
pip install libtea
python -m libtea https://pypi.sbomify.com pkg:pypi/genomeshader@0.3.1
```

Machine-readable copy of this page: https://pypi.sbomify.com/package/genomeshader/0.3.1.json

---
From pypi-tea by sbomify: https://pypi.sbomify.com/package/genomeshader/0.3.1